| P | # | Player | Born | Height | Weight | Contract | |
|---|---|---|---|---|---|---|---|
| GK | Davy Roef | 1994-02-06 | 187 | 84 | 2017 jun | ||
| GK | Silvio Proto | 1983-05-23 | 187 | 72 | 2017 jun | ||
| GK | Thomas Kaminski | 1992-10-23 | 188 | 70 | 2016-06-30 | ||
| D | Ablaye Seck | 1988-03-10 | 189 | ||||
| D | Anthony Vanden Borre | 1987-10-24 | 185 | 78 | 2017-06-30 | ||
| D | Behrang Safari | 1985-02-09 | 181 | 74 | 2020-12-31 | ||
| D | Bram Nuytinck | 1990-05-04 | 183 | 75 | 2021-06-30 | ||
| D | Denis Odoi | 1988-05-27 | 177 | 79 | |||
| D | Hawsawi Osama | 1984-03-31 | 188 | 83 | |||
| D | Jordan Lukaku | 1994-07-25 | 183 | 77 | 2019-06-30 | ||
| D | Marcin Wasilewski | 1980-06-09 | 186 | 88 | 2017-06-30 | ||
| D | Michael Heylen | 1994-01-03 | 187 | 71 | 2016 jun | ||
| D | Olivier Deschacht | 1981-02-16 | 186 | 75 | 2015 jun | ||
| D | Roland Juhász | 1983-07-01 | 193 | 80 | 2018-06-30 | ||
| M | Bedi Mbenza | 1984-09-11 | 182 | ||||
| M | Cheikhou Kouyaté | 1989-12-21 | 192 | 75 | 2021-06-30 | ||
| M | Demy de Zeeuw | 1983-05-26 | 174 | 71 | 2015 jun | ||
| M | Dennis Praet | 1994-05-14 | 180 | 70 | 2021-06-30 | ||
| M | Fernando Canesin | 1992-02-27 | 176 | 68 | Loan | ||
| M | Guillaume Gillet | 1984-03-09 | 186 | 77 | |||
| M | Kanu | 1987-09-23 | 193 | 86 | 2016 Jun | ||
| M | Lucas Biglia | 1986-01-30 | 169 | 63 | 2020-06-30 | ||
| M | Massimo Bruno | 1993-09-17 | 178 | 74 | 2019-06-30 | ||
| M | Mehdi Tarfi | 1993-07-05 | 177 | ||||
| M | Oleksandr Yakovenko | 1987-07-23 | 182 | 68 | 2016-06-30 | ||
| M | Reynaldo | 1989-08-24 | 172 | 63 | |||
| M | Ronald Vargas | 1986-12-02 | 175 | 67 | 2014 | ||
| M | Sacha Kljestan | 1985-09-09 | 185 | 77 | 2016 jun | ||
| F | Cyriac | 1990-08-15 | 174 | 66 | 2016 jun | ||
| F | Dieumerci Mbokani | 1985-11-22 | 185 | 73 | 2017-06-30 | ||
| F | Guillermo Molins | 1988-09-26 | 186 | 83 | 2021-12-31 | ||
| F | Matías Suárez | 1988-05-09 | 182 | 75 | 2017 jun | ||
| F | Milan Jovanovic | 1981-04-18 | 183 | 73 | |||
| F | Samuel Armenteros | 1990-05-27 | 181 | 80 | 2020-06-30 | ||
| F | Tom De Sutter | 1985-07-03 | 192 | 88 | 2019-06-30 |
| Date | Player | From | To | Status | Src |
|---|---|---|---|---|---|
| 10.Jul | Isaac Kiese Thelin (F) | Kasimpasa SK | RSC Anderlecht | Confirmed | |
| 3.Feb | Isaac Kiese Thelin (F) | RSC Anderlecht | Kasimpasa SK | Confirmed | |
| 8.Dec | Isaac Kiese Thelin (F) | Malmö FF | RSC Anderlecht | Confirmed | |
| 9.Jan | Isaac Kiese Thelin (F) | RSC Anderlecht | Malmö FF | Confirmed | |
| 30.Jun | Henry Onyekuru (F) | RSC Anderlecht | Everton FC | Confirmed | |
| 30.Jun | Robert Beric (F) | RSC Anderlecht | AS Saint Etienne | Confirmed | |
| 31.May | Matz Sels (GK) | RSC Anderlecht | Newcastle United | Confirmed | |
| 30.Jun | Aaron Leya Iseka (F) | Olympique de Marseille | RSC Anderlecht | Confirmed | |
| 30.Jun | Uros Spajic (D) | RSC Anderlecht | Toulouse FC | Confirmed | |
| 30.Jun | Sebastien De Maio (D) | ACF Fiorentina | RSC Anderlecht | Confirmed |